Managing Multiorgan Disease in Acute-On-Chronic Liver Failure; Improving Critical Care Management of the HRS/AKI Patient - This program is supported by an educational grant from Mallinckrodt Pharmaceuticals

Thursday, April 21, 2022

12:00 PM – 1:00 PM US CST

CE: 1.0

Symposium Moderator(s)

Constantine Karvellas, MD, MS, FRCPC,FCCM

Professor
University of Alberta
Edmonton, AB, Canada

No relevant financial relationship(s) to disclose

Symposium Faculty(s)

Ram Subramanian, MBA, MD, FCCM

Professor of Medicine & Surgery
Emory University
Atlanta, Georgia

Consultant - Mallinckrodt
Jody Olson, MD

University of Kansas Hospital Authority
Shawnee, Kansas

No relevant financial relationship(s) to disclose

This session is for critical care medicine professionals involved in managing multiorgan failure arising as a consequence of acute-on-chronic liver failure (ACLF), including hepatorenal syndrome/acute kidney injury (HRS/AKI), and the risks of acute respiratory distress syndrome (ARDS) in patients undergoing albumin revolumization.

This program is supported by an education grant from Mallinckrodt

Learning Objectives:

Discuss the terms cirrhosis, decompensation, and acute-on-chronic liver failure (ACLF), as well as their clinical significance and risk to patient mortality
Review current evidence for the whole-patient management of multiorgan failure arising from ACLF, including risks to renal and respiratory function
Apply evidence-based fluid management protocols to revolumize patients with ascites following large-volume paracentesis in AKI patients to establish a diagnosis of HRS/AKI, while mitigating risks from fluid overload
Intervene with proactive evidence-based vasoconstrictor therapy for patients who meet diagnostic criteria for HRS/AKI based on American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of the Liver (EASL) algorithms
Monitor patients with cirrhosis, ascites, and HRS/AKI for treatment-emergent adverse events that may worsen prognosis