Assistant Professor of Medicine
Perelman School of Medicine, University of Pennsylvania
Philadelphia, Pennsylvania
Michael G. S. Shashaty, MD, MSCE, FCCM, Assistant Professor of Medicine, Perelman School of Medicine, University of Pennsylvania
I am a practicing intensivist and an active clinical and translational investigator with a focus on the acute organ dysfunction syndromes of acute kidney injury (AKI) and the acute respiratory distress syndrome (ARDS) in critical illness and lung transplant populations.
I am the principal investigator of the Lung Transplant Outcomes Group–Acute Kidney Injury (LTOG-AKI) study, a multicenter prospective cohort of lung transplant recipients (n>1800) designed to study the clinical and molecular epidemiology of post-lung transplant AKI. Our goals are to determine the impact of AKI on lung transplant outcomes, identify AKI risk factors to identify at-risk transplant recipients, use biomarkers to elucidate the pathophysiology of post-lung transplant AKI, and ultimately implement patient-targeted preventive and therapeutic strategies to reduce AKI rates and improve patient-centered outcomes. I also direct the ongoing Penn Trauma Organ Dysfunction Study (PETROS), a prospective cohort of critically ill trauma patients (n>1500), and am a co-investigator in Penn’s Molecular Epidemiology of Severe Sepsis in the ICU (MESSI) cohort, for which I lead studies of AKI. My current studies in sepsis and trauma include investigating the relationship of obesity with AKI, circulating cell-free DNA as a mechanistic contributor to AKI and ARDS, and genetic risk factors for AKI. I work with a group of talented critical care clinical and translational researchers and have the opportunity to mentor multiple junior investigators.
I also serve as the Rapid Response Medical Director at the Hospital of the University of Pennsylvania, engaged in an array of efforts to maintain our staff's clinical emergencies proficiency through simulation, enhance electronic capture and analysis of clinical emergencies data, and establish systems for safe and effective delivery of early critical care to decompensating patients.
Disclosure information not submitted.
Monday, April 18, 2022
10:00 AM – 11:00 AM US CST
Monday, April 18, 2022
10:00 AM – 11:00 AM US CST
Tuesday, April 19, 2022
1:00 PM – 2:00 PM US CST
Tuesday, April 19, 2022
1:00 PM – 2:00 PM US CST