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Updates and Future Directions

One-Hour Concurrent Session

Resistance Is Not Futile: Emerging Strategies for the Treatment of Multidrug-Resistant Infections in the ICU

Tuesday, April 19, 2022

1:00 PM – 2:00 PM US CST

CE: 1.0

Concurrent Session Moderator(s)

EE

Evan Ewers, MD, MPH

n/a

No relevant financial relationship(s) to disclose
Charlotte Thomas, DNP,

Chief, Advance Practice, Critical Care Medicine
Scripps Mercy Hospital
Chula Vista

No relevant financial relationship(s) to disclose

Increasing rates of antimicrobial drug resistance in the community and in the ICU imperil our ability to care for patients with sepsis and septic shock. In this session, we will review the clinical features that clinicians can use to guide rational antimicrobial drug use, new and emerging diagnostic tests that help us choose the right drug more rapidly, and the data for novel antimicrobial agents, including beta-lactam/beta-lactamase inhibitors and tetracycline derivates, that may support the care of infected patients in the ICU.

Learning Objectives:

Discuss the epidemiology of highly drug-resistant infections in the ICU, with special emphasis on their impact on morbidity and mortality
Describe current evidence and international guidelines for the treatment of multidrug-resistant bacterial infections, including novel beta-lactam agents and investigational drugs and the role of empiric combination therapy
Define the impact of emerging highly resistant fungal infections in the ICU, illustrate the relevant risk factors for these infections, and examine available antifungal treatment strategies

Presentations:

As Broad as We Need to Be: Empiric Antimicrobial Drug Selection and Clinical Decision-Making at the Bedside
Concurrent Session Faculty: Mojdeh S. Heavner, BCCCP, BCPS, PharmD – University of Maryland School of Pharmacy
Bad Bugs, More Drugs: New Options for Treating Multidrug-Resistant Infections
Concurrent Session Faculty: Christy Forehand, PharmD, BCCCP – Augusta University Medical Center
Beyond Cultures: Biomarkers and Rapid Molecular Tests to Improve Antimicrobial Use
Concurrent Session Faculty: Ryan Maves, MD, FCCM – Wake Forest School of Medicine